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Home >> Antibodies >> Fibroblast growth factor receptor 2 Antibody / FGFR2

Fibroblast growth factor receptor 2 Antibody / FGFR2 (RQ7691)

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  Catalog No Formulation Size Price (USD)  
Image RQ7691 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Flow cytometry testing of human U-2 OS cells with Fibroblast growth factor receptor 2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Fibroblast growth factor receptor 2 antibody.
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Flow cytometry testing of human U-2 OS cells with Fibroblast growth factor receptor 2 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Fibroblast growth factor receptor 2 antibody.
Western blot testing of human 1) MCF7, 2) HeLa and 3) K562 cell lysate with Fibroblast growth factor receptor 2 antibody. Predicted molecular weight: 80-120 kDa. The observed size may be larger due to glycosylation.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P21802
Applications Western blot : 0.5-1ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This Fibroblast growth factor receptor 2 antibody is available for research use only.
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Description

Fibroblast growth factor receptor 2 (FGFR2) is a receptor for fibroblast growth factor encoded on a gene residing on chromosome 10. FGFR2 has also been designated as CD332. FGFR2 is a membrane-spanning tyrosine kinase that serves as a high affinity receptor for several members of the fibroblast growth factor(FGF) family. Its signals are absolutely required for vertebrate limb induction and that an FGFR2 signal is essential for the reciprocal regulation loop between FGF8 and FGF10 during limb induction. FGFR2 contributes to the outgrowth, differentiation, and maintenance of the inner cell mass and raise the possibility that this activity is mediated by FGF4 signals transmitted by FGFR2. The role of early FGF signaling in pregastrulation development as a possible adaptation to mammalian(amniote) embryogenesis is discussed.

Application Notes

Optimal dilution of the Fibroblast growth factor receptor 2 antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids R22-T821) was used as the immunogen for the Fibroblast growth factor receptor 2 antibody.

Storage

After reconstitution, the Fibroblast growth factor receptor 2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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