- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
FEZ1 Antibody / Fasciculation and elongation protein zeta-1 Antibody (FY13525)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
FY13525 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 449 |
|
| Species Reactivity | Mouse, Rat |
| Format | Antigen affinity purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Buffer | Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4. |
| UniProt | Q99689 |
| Applications | Western Blot : 0.5-1ug/ml |
| Limitations | The FEZ1 Antibody / Fasciculation and elongation protein zeta-1 Antibody is available for research use only. |
|
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FEZ1 Antibody / Fasciculation and elongation protein zeta-1 Antibody detects FEZ1, a protein associated with neuronal development and intracellular transport. It is related to the UNC-76 family of proteins involved in axonal organization and functions as an interaction partner for components of the neuronal transport machinery. FEZ1 is not a conventional motor protein; instead, it helps connect molecular partners within complexes that move or organize cellular cargo. Its coiled-coil regions contribute to interactions that are important for protein localization and function.
Neurons rely on coordinated movement of proteins, vesicles, and organelles along long cellular processes. FEZ1 has been implicated in kinesin-associated transport pathways and in processes relevant to axon formation and extension. It also interacts with regulatory proteins that can influence its phosphorylation state and binding relationships. Because axonal development requires both cytoskeletal organization and targeted delivery of materials, FEZ1 occupies a useful position at the interface of these processes. The exact consequences of its interactions can differ according to developmental stage and cellular context. The Fasciculation and elongation protein zeta-1 Antibody designation reflects the full protein name associated with the FEZ1 target.
FEZ1 has been studied in connection with neuronal connectivity and disorders involving altered neural development or function. Some reports have also examined its interactions with proteins outside the core transport machinery, suggesting that its regulatory roles may extend beyond a single pathway. These findings should be interpreted carefully because association with a disease-related protein does not alone establish a causal disease mechanism. FEZ1 is distinct from its related family member FEZ2, and their biological roles should not be assumed to be identical. NSJ Bioreagents offers the FEZ1 Antibody for this neuronal protein. A FEZ1 Antibody is relevant to the molecular organization of axonal transport, neuronal morphology, and intracellular cargo trafficking.
Explore related research targets in our Neuroscience Antibodies collection.
An appropriate dilution of the FEZ1 Antibody / Fasciculation and elongation protein zeta-1 Antibody should be determined empirically before routine use.
The FEZ1 Antibody was generated using a synthetic peptide corresponding to a sequence at the N-terminus of human FEZ1.
The FEZ1 Antibody is stable for up to one month at 4oC after reconstitution. For longer-term storage, aliquot and store at -20oC for up to six months. Do not repeatedly freeze and thaw.
FEZ1 antibody, Fasciculation and elongation protein zeta-1 antibody, fasciculation and elongation protein zeta 1 antibody, Zygin I antibody, Zygin-1 antibody, FEZ1 rabbit polyclonal antibody
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