- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
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FCGR1A Antibody specifically detects CD64/FCGR1A, a surface glycoprotein with high affinity for monomeric IgG, is expressed constitutively on monocytes and macrophages, and can be induced in neutrophils subsequent to IFN-gamma stimulation. It plays a putative role in the initiation of cell-mediated cytotoxicity. Thus far, three genes encoding four distinct CD64 transcripts have been described. CD64/FCGR1A has been shown to associate with signal transducing subunit of the high affinity IgE receptor.
Researchers studying Fc receptor signaling, monocyte activation, and antibody-dependent immune responses may also benefit from the CD64 Antibody / High-Affinity Fc Gamma Receptor page featuring the widely published clone 10.1 and flow cytometry validation in PBMC immune cell populations.
Optimal dilution of the FCGR1A antibody should be determined by the researcher.
A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the FCGR1A antibody.
Aliquot the FCGR1A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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