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Home >> Antibodies >> Fatty Acid Binding Protein 1 Antibody / FABP1

Fatty Acid Binding Protein 1 Antibody / FABP1 [clone FABP1/8521R] (V4875)

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  Catalog No Formulation Size Price (USD)  
Image V4875-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4875-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4875SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recrabbitmono
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IHC staining of FFPE human kidney tissue with Fatty Acid Binding Protein 1 antibody (clone FABP1/8521R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human kidney tissue with Fatty Acid Binding Protein 1 antibody (clone FABP1/8521R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human kidney tissue with Fatty Acid Binding Protein 1 antibody (clone FABP1/8521R). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free Fatty Acid Binding Protein 1 antibody (clone FABP1/8521R) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name FABP1/8521R
Purity Protein A/G affinity
UniProt P07148
Localization Cytoplasm, Nucleus
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This Fatty Acid Binding Protein 1 antibody is available for research use only.
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Description

Fatty acid-binding proteins, designated FABPs, are a family of homologous cytoplasmic proteins that are expressed in a highly tissue-specific manner and play an integral role in the balance between lipid and carbohydrate metabolism. FABPs mediate fatty acid (FA) and/or hydrophobic ligand uptake, transport and targeting within their respective tissues. The mechanisms underlying these actions can give rise to both passive diffusional uptake and protein-mediated transmembrane transport of FAs. FABPs are expressed in adipocytes (A-FABP), brain (B-FABP), epithelium (E-FABP, psoriasis-associated FABP, PA-FABP), striated muscle and heart (H-FABP, mammary-derived growth inhibitor or MDGI), intestine (I-FABP), liver (L-FABP or FABP1), myelin (M-FABP) and testis (T-FABP). FABP1 (L-FABP) expression is modulated by developmental, hormonal, dietary and pharmacological factors, and is required for cholesterol synthesis and metabolism.

Application Notes

Optimal dilution of the Fatty Acid Binding Protein 1 antibody should be determined by the researcher.

Immunogen

A recombinant partial protein sequence (within amino acids 1-127) from the human protein was used as the immunogen for the Fatty Acid Binding Protein 1 antibody.

Storage

Aliquot the Fatty Acid Binding Protein 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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