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Home >> Antibodies >> Factor XIIIa Antibody

Factor XIIIa Antibody [clone SPM180] (V3431)

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  Catalog No Formulation Size Price (USD)  
Image V3431-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V3431-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V3431SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC testing of FFPE human placenta with Factor XIIIa antibody (clone SPM180). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
IHC testing of FFPE human placenta with Factor XIIIa antibody (clone SPM180). Required HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name SPM180
Purity Protein G affinity chromatography
UniProt P00488
Localization Cytoplasmic, secreted
Applications Western blot : 1-2ug/ml
Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This Factor XIIIa antibody is available for research use only.
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Description

Factor XIIIa has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-Factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-Factor XIIIa positivity is also seen in capillary hemagioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.

Application Notes

Titering of the Factor XIIIa antibody may be required for optimal performance.

Immunogen

A human partial recombinant protein corresponding to amino acids 46-181 was used as the immunogen for the Factor XIIIa antibody.

Storage

Store the Factor XIIIa antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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