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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
Titration of the FACL4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 28-56 from the human protein was used as the immunogen for this FACL4 antibody.
Aliquot the FACL4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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