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Home >> Antibodies >> FABP4 Antibody

FABP4 Antibody (R31970)

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  Catalog No Formulation Size Price (USD)  
Image R31970 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 449
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FABP4 Antibody Mouse Intestine IHC. Immunohistochemistry testing of FFPE mouse intestine with FABP4 antibody. HIER: Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to staining.
FABP4 Antibody Rat Intestine IHC. Immunohistochemistry testing of FFPE rat intestine with FABP4 antibody. HIER: Boil the paraffin sections in pH 6, 10mM citrate buffer for 20 minutes and allow to cool prior to staining.
FABP4 Antibody Rat Mouse WB. Western blot testing of 1) human RT4, 2) rat heart and 3) mouse heart lysate with FABP4 antibody. Expected molecular weight ~15 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P15090
Localization Cytoplasmic
Applications Western Blot : 0.1-0.5ug/ml
Immunohistochemistry (FFPE) : 0.5-1ug/ml
Limitations This FABP4 antibody is available for research use only.
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Description

Fatty acid binding proteins (FABPs) are small cytoplasmic proteins that are expressed in a highly tissue-specific manner and bind to fatty acids such as oleic and retinoic acid. Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and macrophages, and integrates inflammatory and metabolic responses. Studies in aP2-deficient mice have shown that this lipid chaperone has a significant role in several aspects of metabolic syndrome, including type 2 diabetes and atherosclerosis. It regulates allergic airway inflammation and may provide a link between fatty acid metabolism and asthma.

Additional studies involving adipocyte biology, lipid transport signaling, and metabolic-inflammatory pathway regulation may benefit from our FABP4 antibody page featuring clone FABP4/4424 with HuProt protein microarray specificity validation.

Application Notes

Optimal dilution of the FABP4 antibody should be determined by the researcher.

Immunogen

Amino acids KLVSSENFDDYMKEVGVGFATRKVAGMAKPN of human FABP4 were used as the immunogen for the FABP4 antibody.

Storage

After reconstitution, the FABP4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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