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Home >> Antibodies >> ETV6 Antibody / Tel

ETV6 Antibody / Tel (RQ4018)

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  Catalog No Formulation Size Price (USD)  
Image RQ4018 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human 1) placenta, 2) HeLa, 3) 22RV1, 4) SKOV and 5) A549 lysate with ETV6 antibody at 0.5ug/ml. Predicted molecular weight ~53 kDa.
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Western blot testing of human 1) placenta, 2) HeLa, 3) 22RV1, 4) SKOV and 5) A549 lysate with ETV6 antibody at 0.5ug/ml. Predicted molecular weight ~53 kDa.
IHC testing of FFPE human breast cancer tissue with ETV6 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.
IHC testing of FFPE human lung cancer tissue with ETV6 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.
IHC testing of FFPE mouse small intestine tissue with ETV6 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.
IHC testing of FFPE rat small intestine tissue with ETV6 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P41212
Localization Nuclear
Applications Western Blot : 0.5-1ug/ml
IHC (FFPE) : 1-2ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This ETV6 antibody is available for research use only.
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Description

Transcription factor ETV6 is a protein that in humans is encoded by the ETV6 gene. This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma.

Application Notes

Optimal dilution of the ETV6 antibody should be determined by the researcher.

Immunogen

A recombinant human partial protein corresponding to amino acids E327-Q448 was used as the immunogen for the ETV6 antibody.

Storage

After reconstitution, the ETV6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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