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- Tel: 858.663.9055
- Email: info@nsjbio.com
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ETS1 proto-oncogene is an important transcription factor that plays a role in cell proliferation and differentiation. ETS1 is related to the growth of carcinoma cells by its regulation of the transcription of matrix metalloproteinases and urokinase-type plasminogen activator.The processes of tumor invasion and metastasis depend on the increased proteolytic activity of the invading tumor cells that may involve matrix metalloproteinases, cathepsins B and D and plasminogen activator in the metastatic cascade. ETS1 is preferentially expressed in lymphoid cells, where it is essential for the maintenance of the normal pool of resting T and B cells.ETS1 expression level and distribution are differentially controlled in resting, activated and apoptotic lymphocytes.
Optimal dilution of the ETS1 antibody should be determined by the researcher.
A recombinant human partial protein (amino acids 137-230) was used as the immunogen for the ETS1 antibody.
Store the ETS1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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