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Home >> Antibodies >> Estrogen Receptor alpha Antibody

Estrogen Receptor alpha Antibody [clone ESR1/420] (V8779)

  Catalog No Formulation Size Price (USD)  
Image V8779-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V8779-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V8779SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Bulk quote request
SDS-PAGE analysis of purified, BSA-free Estrogen Receptor alpha antibody (ESR1/420) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name ESR1/420
Purity Protein A/G affinity
UniProt P03372
Localization Nuclear
Applications Flow cytometry : 1-2ug/million cells
Immunofluorescence : 1-2ug/ml
Limitations This Estrogen Receptor alpha antibody is available for research use only.
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Description

This mAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.

Application Notes

Optimal dilution of the Estrogen Receptor alpha antibody should be determined by the researcher.

Immunogen

A portion of amino acids 290-560 was used as the immunogen for the Estrogen Receptor alpha antibody. The epitope of this mAb is between amino acids 300-550.

Storage

Aliquot the Estrogen Receptor alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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