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Home >> Antibodies >> Estrogen Receptor alpha Antibody

Estrogen Receptor alpha Antibody [clone ER506] (V2113CF488)

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  Catalog No Formulation Size Price (USD)  
Image V2113CF488-100T 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 Tests 519
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Availability 1-3 business days
Species Reactivity Human
Format CF488 Conjugate
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name ER506
Purity Protein G affinity chromatography
UniProt P03372
Localization Nuclear
Applications Flow cytometry : 5ul per test per one 10^6 cells in 0.1ml or 5ul per 100ul of whole blood
Immunofluorescence :
Limitations This Estrogen Receptor alpha antibody is available for research use only.
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Description

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.

Application Notes

Optimal dilution of the Estrogen Receptor alpha antibody should be determined by the researcher.

Immunogen

Recombinant human ER alpha protein (aa 2-185) was used as the immunogen.

Storage

Store the Estrogen Receptor alpha antibody at 2-8oC, protected from light.

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