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Home >> Antibodies >> Estrogen Receptor alpha Antibody CF488 Conjugate

Estrogen Receptor alpha Antibody CF488 Conjugate [clone ER506] (V2113CF488)

  Catalog No Formulation Size Price (USD)  
Image V2113CF488-100T 500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 Tests 559
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Estrogen Receptor alpha Antibody CF488 Conjugate IF. Immunofluorescent staining of methanol-fixed human MCF7 cells with Estrogen Receptor alpha Antibody CF488 conjugate (clone ER506, green) and Reddot nuclear stain (red).
Availability 1-3 business days
Species Reactivity Human
Format CF488 Conjugate
Host Mouse
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name ER506
Purity Protein G affinity chromatography
UniProt P03372
Localization Nuclear
Applications Flow Cytometry : 1-2ug/million cells
Immunofluorescence : 1-3ug/ml
Limitations This Estrogen Receptor alpha Antibody CF488 Conjugate is available for research use only.
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Description

This Estrogen Receptor alpha Antibody CF488 Conjugate is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. It strongly stains nuclei of epithelial cells in breast carcinomas.

For a microarray-validated Estrogen receptor alpha antibody supporting high-specificity detection, see clone ESR1/3557.

Application Notes

Optimal dilution of the Estrogen Receptor alpha Antibody CF488 Conjugate should be determined by the researcher.

Immunogen

Recombinant human ER alpha protein (aa 2-185) was used as the immunogen.

Storage

Store the Estrogen Receptor alpha antibody at 2-8oC, protected from light.

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