- Tel: 858.663.9055
-
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
ERMAP Antibody / Erythroid membrane-associated protein Antibody (FY13611)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
FY13611 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 449 |
|
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Host | Rabbit |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Buffer | Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4. |
| UniProt | Q96PL5 |
| Applications | Western Blot : 0.5-1ug/ml ELISA : 0.1-0.5 ug/ml |
| Limitations | This ERMAP Antibody / Erythroid membrane-associated protein Antibody is provided for laboratory research use only. |
|
Review this product on BioCompare and get a $20 Amazon gift card
|
ERMAP Antibody / Erythroid membrane-associated protein Antibody recognizes ERMAP, a protein with important roles in cellular physiology. ERMAP encodes erythroid membrane-associated protein, a type I membrane glycoprotein expressed prominently during erythroid development. The protein contains an extracellular immunoglobulin-like domain and an intracellular region associated with signaling-related protein motifs. ERMAP is also the carrier of antigens belonging to the Scianna blood group system, giving it a recognized role in transfusion medicine.
Variation in the ERMAP gene can alter Scianna blood group antigens on the red blood cell surface. Although antibodies against these antigens are uncommon, their recognition can be relevant in blood group typing and investigations of alloimmune responses. This connection illustrates how a single membrane protein can be significant both for erythrocyte biology and for the antigenic diversity encountered during transfusion. Erythroid membrane-associated protein Antibody is a useful designation for this molecular target.
ERMAP has also been described as a member of the butyrophilin-related immunoglobulin superfamily. Its domain organization suggests potential involvement in cell-surface interactions, but the precise physiological signaling functions of ERMAP are not as well established as its identity as a blood group antigen carrier. Expression during erythroid maturation raises questions about how the protein contributes to membrane organization or communication between developing blood cells and their environment.
As erythroid precursors mature, their plasma membranes undergo extensive remodeling to support the specialized functions of circulating erythrocytes. ERMAP is one component of this changing surface proteome. Its study connects molecular genetics, erythroid differentiation, membrane-protein diversity, and the clinical significance of inherited blood group variation. NSJ Bioreagents provides ERMAP Antibody for research into the molecular biology of ERMAP. An ERMAP Antibody supports investigation of the biological processes associated with this protein.
Explore related research targets in our Immunology Antibodies collection.
The recommended approach is to establish the optimal working dilution of the ERMAP Antibody / Erythroid membrane-associated protein Antibody through preliminary testing.
The ERMAP Antibody was generated using e. coli-derived human ERMAP recombinant protein (amino acids T58-K213).
Store the reconstituted ERMAP Antibody at 4oC for up to one month. For long-term storage, divide into aliquots and keep at -20oC for up to six months. Avoid repeated freeze-thaw cycles.
ERMAP antibody, Erythroid membrane-associated protein antibody, erythroblast membrane associated protein (Scianna blood group) antibody, hERMAP antibody, PRO2801 antibody, Radin blood group antigen antibody, RD antibody, SC antibody, Scianna blood group antigen antibody
Your bulk quote request has been submitted successfully!
Please contact us if you have any questions.
Powered by Bioz