ERBB3 Antibody / EGFR Family Receptor Antibody (R30980)

ERBB3 Antibody Knockout Validation WB. Western blot analysis was performed using ERBB3 Antibody on lane 1: human A549 wild-type whole cell lysate and lane 2: human A549 ERBB3 knockout whole cell lysate. A strong immunoreactive band is detected at approximately 180 kDa in the wild-type sample, while the band is absent in the ERBB3 knockout lysate, confirming the specificity of the antibody for ERBB3. GAPDH served as the loading control and demonstrates equivalent protein loading between samples. This ERBB3 Antibody / EGFR Family Receptor Antibody has been validated using a knockout model, providing confidence for studies of EGFR family signaling, neuregulin-mediated receptor activation, and cancer-associated signal transduction.

ERBB3 Antibody Human Breast Cancer Cell WB. Western blot analysis was performed using ERBB3 Antibody on lane 1: human MCF-7, lane 2: human MDA-MB453, lane 3: human 293T, and lane 4: human T-47D whole cell lysates. A prominent immunoreactive band is detected at approximately 180 kDa in MCF-7, MDA-MB453, and T-47D cells, while little to no ERBB3 expression is observed in 293T cells. The detected band is consistent with the heavily glycosylated mature ERBB3 receptor commonly observed at a higher apparent molecular weight than its predicted size. This ERBB3 Antibody / EGFR Family Receptor Antibody is well suited for Western blot studies of EGFR family signaling, receptor dimerization, neuregulin-mediated activation, and cancer biology.