Ephrin Receptor B3 Antibody / EPHB3 (RQ8119)

Description

Ephrin Receptor B3 (EPHB3) is a member of the Eph receptor tyrosine kinase family, which mediates cell–cell communication through binding to membrane-bound ephrin-B ligands. EPHB3 plays critical roles in developmental processes such as axon guidance, tissue boundary formation, and neural progenitor positioning. Upon ligand binding, EPHB3 activates bidirectional signaling that influences cytoskeletal dynamics, adhesion, and cell migration.

EPHB3 is expressed in the developing nervous system, intestinal epithelium, and select adult tissues, where it contributes to spatial organization and cell fate determination. Its signaling is involved in maintaining tissue architecture and guiding cellular interactions in both embryonic and mature systems, making it a useful marker in developmental and cellular signaling studies.

The Ephrin Receptor B3 antibody is a valuable tool for detecting endogenous EPHB3 in applications such as western blot, immunohistochemistry, and immunofluorescence. Researchers use the Ephrin Receptor B3 antibody from NSJ Bioreagents to study receptor expression, track tissue-specific localization, and investigate ephrin-mediated signaling events. With high specificity and consistent performance, the Ephrin Receptor B3 antibody supports detailed analysis of cell communication, neural development, and receptor tyrosine kinase pathways.

Application Notes

Optimal dilution of the Ephrin Receptor B3 antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids H275-Q554) was used as the immunogen for the Ephrin Receptor B3 antibody.

Storage

After reconstitution, the Ephrin Receptor B3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.