Eotaxin 3 Antibody / CCL26 (R31495)

Eotaxin-3 Antibody Human Cancer Cell Lines WB. Western blot analysis of CCL26 expression was performed using anti-Eotaxin-3 antibody in lysates from human COLO320, A549, and HT1080 cells. Eotaxin-3, also known as CCL26, is a CC chemokine that mediates eosinophil recruitment and contributes to allergic inflammation and Th2 immune responses. Lane 1: COLO320 lysate. Lane 2: A549 lysate. Lane 3: HT1080 lysate. A specific immunoreactive band is detected at approximately 11 kDa in all three cell lines, corresponding to the predicted molecular weight of Eotaxin-3. Similar expression across colon carcinoma, lung carcinoma, and fibrosarcoma cells is consistent with the broad involvement of CCL26 in inflammatory signaling and tumor-associated immune responses. These results support the utility of Eotaxin-3 Antibody for studies of chemokine biology, eosinophil recruitment, and inflammatory disease.

Eotaxin-3 Antibody Human Lung Cancer IHC. IHC staining of FFPE human lung cancer tissue with Eotaxin-3 antibody demonstrated cytoplasmic and membranous staining in malignant epithelial cells and surrounding stromal elements, consistent with the expression pattern of Eotaxin-3 (CCL26), a CC chemokine involved in eosinophil recruitment and Th2-mediated inflammatory responses. Eotaxin-3 participates in immune signaling through CCR3 and contributes to the inflammatory tumor microenvironment. The staining pattern observed is consistent with the known expression of CCL26 in epithelial tissues and its role in regulating interactions between tumor cells and infiltrating immune cells. Immunostaining supports the utility of Eotaxin-3 Antibody for studies of chemokine biology, allergic inflammation, eosinophil trafficking, and tumor-associated immune responses.

Eotaxin-3 Antibody Human Breast Cancer IHC. IHC staining of FFPE human breast cancer tissue with Eotaxin-3 antibody demonstrated cytoplasmic and membranous staining in malignant epithelial cells and surrounding stromal components, consistent with the expression pattern of Eotaxin-3 (CCL26), a CC chemokine that regulates eosinophil recruitment and Th2-associated immune responses. Eotaxin-3 participates in inflammatory signaling through CCR3 and contributes to communication between tumor cells and the immune microenvironment. The staining observed in both neoplastic and stromal compartments is consistent with reported expression of CCL26 in epithelial tumors and inflammatory tissues. These results support the utility of Eotaxin-3 Antibody for studies of chemokine biology, allergic inflammation, eosinophil trafficking, and tumor-associated immune responses.