- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Endothelin B Receptor Antibody / EDNRB (F54884)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54884-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F54884-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | P24530 |
| Applications | Flow cytometry : 1:10-1:50 (1x10e6 cells) Immunofluorescence : 1:10-1:50 Immunohistochemistry (FFPE) : 1:10-1:50 Western blot : 1:500-1:1000 |
| Limitations | This Endothelin B Receptor antibody is available for research use only. |
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EDNRB is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene.
The stated application concentrations are suggested starting points. Titration of the Endothelin B Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 409-439 from the human protein was used as the immunogen for the Endothelin B Receptor antibody.
Aliquot the Endothelin B Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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