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- Email: info@nsjbio.com
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CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
Optimal dilution of the Emmprin antibody should be determined by the researcher.
Native human leukocytes were used as the immunogen for the Emmprin antibody.
Store the Emmprin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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