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Home >> Antibodies >> Emmprin Antibody

Emmprin Antibody [clone CB43] (V2875)

  Catalog No Formulation Size Price (USD)  
Image V2875-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V2875-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V2875SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgM, kappa
Clone Name CB43
Purity PEG precipitation
UniProt P35613
Localization Cell surface
Applications Flow cytometry : 0.5-1ug/10^6 cells
Immunofluorescence : 0.5-1ug/ml
Limitations This Emmprin antibody is available for research use only.
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Description

CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.

Application Notes

Optimal dilution of the Emmprin antibody should be determined by the researcher.

Immunogen

Native human leukocytes were used as the immunogen for the Emmprin antibody.

Storage

Store the Emmprin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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