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Home >> Antibodies >> EIF4B Antibody

EIF4B Antibody (F40110)

  Catalog No Formulation Size Price (USD)  
Image F40110-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40110-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of EIF4B antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the EIF4B gene (2).
IHC analysis of FFPE human breast carcinoma tissue stained with EIF4B antibody
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P23588
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This EIF4B antibody is available for research use only.
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Description

EIF4B is required for the binding of mRNA to ribosomes. It functions in close association with EIF4-F and EIF4-A by binding near the 5'- terminal cap of mRNA in presence of EIF-4F and ATP. It also promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F

Application Notes

Titration of the EIF4B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 400-429 from the human protein was used as the immunogen for this EIF4B antibody.

Storage

Aliquot the EIF4B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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