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Home >> Antibodies >> EGF Receptor Antibody

EGF Receptor Antibody [clone 688CT33.1.3] (F40405)

  Catalog No Formulation Size Price (USD)  
Image F40405-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 389
Image
F40405-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 155
Immunohistochemical analysis of paraffin-embedded human esophagus using EGF Receptor antibody at 1:25 dilution.
Immunohistochemical analysis of paraffin-embedded human stomach using EGF Receptor antibody at 1:25 dilution.
Immunohistochemical analysis of paraffin-embedded mouse esophagus using EGF Receptor antibody at 1:25 dilution.
Immunohistochemical analysis of paraffin-embedded rat esophagus using EGF Receptor antibody at 1:25 dilution.
Western blot analysis of lysate from A431, MCF-7 cell line (left to right) using EGF Receptor antibody at 1:1000 for each lane. Expected molecular weight: ~134/170 kDa (unmodified/glycosylated).
EGF Receptor antibody western blot analysis in HeLa lysate. Expected molecular weight: ~134/170 kDa (unmodified/glycosylated).
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1
Clone Name 688CT33.1.3
Purity Purified
UniProt P00533
Localization Cytoplasmic, membranous
Applications IHC (Paraffin) : 1:25
Western blot : 1:1000
Limitations This EGF Receptor antibody is available for research use only.
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Description

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Application Notes

Titration of the EGF Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1163-1191 from the human protein was used as the immunogen for this EGF Receptor antibody.

Storage

Aliquot the EGF Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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