- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
EDA Antibody (R30638)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R30638 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
|
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal |
| UniProt | Q92838 |
| Applications | Western blot : 0.5-1ug/ml |
| Limitations | This EDA antibody is available for research use only. |
|
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Anhidrotic ectodermal dysplasia is an X-linked recessive disorder which affects ectodermal structures. Ectodysplasin-A, the protein encoded by the EDA gene, is a member of the tumor necrosis factor ligand superfamily that forms a collagen triple helix, suggesting functions in signal transduction and cell adhesion. Wnt signaling controls EDA gene expression, but Ectodysplasin-A does not feedback on the Wnt pathway.
The stated application concentrations are suggested starting amounts. Titration of the EDA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
An amino acid sequence from the middle region of human EDA (HLQGQGSAIQVKNDLS) was used as the immunogen for this EDA antibody (100% homologous in human, mouse and rat).
After reconstitution, the EDA antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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