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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.
Titration of the DR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 356-385 from the human protein was used as the immunogen for this DR6 antibody.
Aliquot the DR6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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