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Home >> Antibodies >> Doublecortin Antibody / DBCN / DCX

Doublecortin Antibody / DBCN / DCX [clone AOAD-4] (RQ4745)

  Catalog No Formulation Size Price (USD)  
Image RQ4745 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of rat C6 cell lysate with Doublecortin antibody. Predicted molecular weight: 40-50 kDa.
Availability 1-2 weeks
Species Reactivity Human, Rat
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AOAD-4
Purity Affinity purified
UniProt O43602
Applications Western blot : 1:500-1:2000
Limitations This Doublecortin antibody is available for research use only.
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Description

The neuronal migration protein Doublecortin is a microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. [UniProt]

Application Notes

Optimal dilution of the Doublecortin antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Doublecortin / DCX was used as the immunogen for the Doublecortin antibody.

Storage

Store the Doublecortin antibody at -20oC.

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