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Home >> Antibodies >> Dnmt2 Antibody

Dnmt2 Antibody (F40791)

  Catalog No Formulation Size Price (USD)  
Image F40791-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40791-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of Dnmt2 antibody and HL-60 cell lysate
IHC analysis of FFPE human hepatocarcinoma stained with the Dnmt2 antibody
Availability 1-3 business days
Species Reactivity Human, Mouse
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt O55055
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This Dnmt2 antibody is available for research use only.
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  • Applications : WB, IHC, ELISA
    Reactivity : Human, Mouse

Description

Dnmt2 does not appear to be active as a DNA methyltransferase; however, its strong binding to DNA suggests that it may mark specific sequences in the genome by binding to DNA through the specific target-recognizing motif. Dnmt2 is strongly expressed in thymus, testis, and at much lower levels in spleen, lung, brain, heart, kidney, liver, skeletal muscle and embryonic stem cells. This protein belongs to the 5-cystosine methyltransferase family.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Dnmt2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 201-230 from the mouse protein was used as the immunogen for this Dnmt2 antibody.

Storage

Store at 4oC for up to one month. For long term, aliquot the Dnmt2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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