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- Tel: 858.663.9055
- Email: info@nsjbio.com
DNA ligase 3 is an enzyme that, in humans, is encoded by the LIG3 gene. This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Optimal dilution of the DNA Ligase 3 antibody should be determined by the researcher.
Recombinant human protein (amino acids D297-D963) was used as the immunogen for the DNA Ligase 3 antibody.
After reconstitution, the DNA Ligase 3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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