• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Home >> Antibodies >> Distal-Less Homeobox 5 Antibody / DLX-5 Antibody

Distal-Less Homeobox 5 Antibody / DLX-5 Antibody (FY13481)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image FY13481 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 449
Bulk quote request
Distal-Less Homeobox 5 Antibody Rat and Mouse Brain WB. Western blot analysis of Distal-Less Homeobox 5 Antibody using lysates from 1) rat brain and 2) mouse brain. Samples (30 ug/lane) were separated on a 10% SDS-PAGE gel under reducing conditions, transferred to a nitrocellulose membrane, and probed with Distal-Less Homeobox 5 Antibody (0.5 ug/mL), followed by an HRP-conjugated secondary antibody and ECL detection. A specific band is detected at approximately 33 kDa in both rat and mouse brain lysates, consistent with the predicted molecular weight of DLX5 (approximately 32 kDa). These results demonstrate that Distal-Less Homeobox 5 Antibody, a DLX-5 Antibody, specifically detects endogenous DLX5 across rodent brain tissues.
Species Reactivity Mouse, Rat
Format Lyophilized
Host Rabbit
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P68104
Applications Western Blot : 0.5-1ug/ml
Limitations This Distal-Less Homeobox 5 Antibody / DLX-5 Antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

  • Applications : WB, ELISA (peptide)
    Reactivity : Human
    Pred. Reactivity : Mouse, Rat, Cow
  • Applications : IHC-P, WB
    Reactivity : Human

Description

Distal-Less Homeobox 5 Antibody recognizes DLX5, a homeobox-containing transcription factor that directs gene expression during embryonic development and tissue differentiation. As a member of the distal-less family of developmental regulators, DLX5 controls transcriptional programs required for craniofacial patterning, skeletal formation, limb development, and the maturation of multiple epithelial and mesenchymal tissues. By binding specific DNA regulatory elements, DLX5 coordinates lineage commitment and cellular differentiation throughout development. Consequently, Distal-Less Homeobox 5 Antibody is widely used to investigate developmental gene regulation and tissue-specific differentiation pathways.

DLX5 is best known for its critical role in osteoblast differentiation and bone formation. It functions upstream of key osteogenic regulators, including RUNX2, and promotes the expression of genes required for extracellular matrix production and mineralization. DLX5 also contributes to tooth development, neural crest differentiation, inner ear morphogenesis, and bone morphogenetic protein signaling. Because of these diverse biological functions, Distal-Less Homeobox 5 Antibody is valuable for studies of skeletal biology, regenerative medicine, stem cell differentiation, and developmental signaling. Researchers also employ DLX-5 Antibody to investigate mechanisms governing lineage specification and tissue regeneration.

Altered DLX5 expression has been reported in several human malignancies, including breast, ovarian, lung, prostate, and endometrial cancers, where abnormal transcriptional regulation may contribute to tumor progression, proliferation, migration, and epithelial-to-mesenchymal transition. In addition, mutations or dysregulated expression of DLX5 have been associated with developmental abnormalities affecting craniofacial structures, hearing, and skeletal formation. These findings have expanded the use of Distal-Less Homeobox 5 Antibody in cancer biology, developmental genetics, and translational research aimed at understanding tissue-specific transcriptional control.

NSJ Bioreagents offers Distal-Less Homeobox 5 Antibody products validated for research applications to support reliable detection of DLX5 across multiple experimental platforms. Whether performing Western blotting, immunohistochemistry, immunofluorescence, immunoprecipitation, or flow cytometry, a well-validated DLX-5 Antibody enables accurate analysis of DLX5 expression and localization.

For additional antibodies targeting the DLX5, visit our DLX5 Antibody / Homeobox Transcription Factor Antibody page to explore complementary products, validation data, and application results.

Application Notes

Optimal dilution of the Distal-Less Homeobox 5 Antibody / DLX-5 Antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human DLX-5 protein (amino acids M1-G228) was used as the immunogen for the Distal-Less Homeobox 5 Antibody.

Storage

After reconstitution, the Distal-Less Homeobox 5 Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Alternate Names

Distal-Less Homeobox 5 antibody, DLX-5 antibody, DLX5 antibody, Homeobox Protein DLX5 antibody, Distal-Less Related Homeobox 5 antibody, Homeobox Transcription Factor antibody

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.