Desmin Antibody / Muscle Intermediate Filament Marker [clone DES/3255] (V9390)

Desmin Antibody Cardiac Muscle IHC. Immunohistochemistry staining of FFPE human cardiac muscle tissue using Desmin antibody (clone DES/3255) demonstrates strong, diffuse cytoplasmic staining throughout cardiomyocytes, consistent with the abundant expression of Desmin intermediate filaments within cardiac muscle. Desmin is a type III intermediate filament protein that forms an essential component of the muscle cytoskeleton, providing structural support and helping maintain the organization of contractile elements within muscle cells. The widespread staining observed in cardiac muscle fibers is consistent with the established role of Desmin as a highly sensitive marker of muscle differentiation and muscle lineage identification. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

Desmin Antibody Skeletal Muscle IHC. Immunohistochemistry staining of FFPE human skeletal muscle tissue using Desmin antibody (clone DES/3255) demonstrates strong, diffuse cytoplasmic staining throughout skeletal myofibers, consistent with the abundant expression of Desmin within differentiated muscle cells. Desmin is a type III intermediate filament protein that forms an essential component of the muscle cytoskeleton, helping maintain structural integrity and organization of contractile elements. The inset negative control, in which PBS was substituted for the primary antibody, shows no specific staining and supports the specificity of the observed immunoreactivity. The staining pattern is consistent with the established role of Desmin as a sensitive marker of skeletal muscle differentiation and muscle lineage identification. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

Desmin Antibody Prostate Tissue IHC. Immunohistochemistry staining of FFPE human prostate tissue with Desmin antibody (clone DES/3255) at 2ug/ml. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

Desmin Antibody Dog Smooth Muscle IHC. Immunohistochemistry staining of FFPE dog smooth muscle tissue using Desmin antibody (clone DES/3255) demonstrates distinct cytoplasmic staining within smooth muscle cells, consistent with expression of Desmin in contractile mesenchymal tissues. Desmin is a type III intermediate filament protein that forms an essential component of the muscle cytoskeleton and contributes to the structural organization and mechanical integrity of muscle cells. The observed staining pattern is consistent with the established role of Desmin as a marker of smooth muscle differentiation and highlights the cross-species utility of clone DES/3255 for veterinary and comparative pathology applications. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

Desmin Antibody Cat Smooth Muscle IHC. Immunohistochemistry staining of FFPE cat smooth muscle tissue using Desmin antibody (clone DES/3255) demonstrates widespread cytoplasmic staining within smooth muscle cell populations, consistent with expression of Desmin intermediate filaments in contractile tissues. Desmin is a type III intermediate filament protein that serves as a key structural component of the muscle cytoskeleton, helping maintain cellular architecture and mechanical stability. The observed staining pattern is consistent with the established role of Desmin as a marker of smooth muscle differentiation and supports the utility of clone DES/3255 for veterinary pathology, comparative biology, and muscle lineage identification studies. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

Desmin Antibody Horse Smooth Muscle IHC. Immunohistochemistry staining of FFPE horse smooth muscle tissue using Desmin antibody (clone DES/3255) demonstrates strong cytoplasmic staining within smooth muscle cell populations, consistent with the abundant expression of Desmin intermediate filaments in contractile tissues. Desmin is a type III intermediate filament protein that forms a critical component of the muscle cytoskeleton, helping maintain structural integrity and organization of muscle cells. The observed staining pattern is consistent with the established role of Desmin as a marker of smooth muscle differentiation and further demonstrates the cross-species reactivity of clone DES/3255 in veterinary and comparative pathology applications. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

Desmin Antibody Cow Small Intestine IHC. Immunohistochemistry staining of FFPE cow small intestine tissue using Desmin antibody (clone DES/3255) demonstrates strong cytoplasmic staining of smooth muscle fibers within the intestinal wall, consistent with expression of Desmin in contractile mesenchymal tissues. Desmin is a type III intermediate filament protein that forms an essential component of the muscle cytoskeleton, helping maintain structural integrity and alignment of contractile elements within muscle cells. The observed staining pattern highlights the utility of Desmin as a marker of smooth muscle differentiation and supports the cross-species reactivity of clone DES/3255 for veterinary pathology, comparative biology, and muscle lineage studies. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

SDS-PAGE analysis of purified, BSA-free Desmin antibody (clone DES/3255) as confirmation of integrity and purity.