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Home >> Antibodies >> Cytokeratin 3 Antibody / KRT3

Cytokeratin 3 Antibody / KRT3 [clone KRT3/2130] (V7909)

  Catalog No Formulation Size Price (USD)  
Image V7909-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7909-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7909SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated
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IHC staining of FFPE human skin with Cytokeratin 3 antibody (clone KRT3/2130). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human ovary with Cytokeratin 3 antibody (clone KRT3/2130). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using Cytokeratin 3 antibody (clone KRT3/2130). These results demonstrate the foremost specificity of the KRT3/2130 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
SDS-PAGE analysis of purified, BSA-free Cytokeratin 3 antibody (clone KRT3/2130) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name KRT3/2130
Purity Protein G affinity chromatography
UniProt P12035
Localization Cytoplasmic
Applications Immunohistochemistry (FFPE) : 1-2ug/ml
Limitations This Cytokeratin 3 antibody is available for research use only.
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Description

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins, which are arranged in pairs of heterotypic keratin chains co-expressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the corneal epithelium with family member KRT12 and mutations in these genes have been associated with Meesmann's Corneal Dystrophy.

Application Notes

Optimal dilution of the Cytokeratin 3 antibody should be determined by the researcher.

Immunogen

A recombinant full-length human protein was used as the immunogen for this Cytokeratin 3 antibody.

Storage

Store the Cytokeratin 3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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