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Home >> Antibodies >> Cytokeratin 19 Antibody / KRT19

Cytokeratin 19 Antibody / KRT19 [clone CCO-11] (RQ5258)

  Catalog No Formulation Size Price (USD)  
Image RQ5258 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of human HepG2 cell lysate with Cytokeratin 19 antibody. Expected molecular weight: 40-43 kDa.
IHC staining of FFPE rat colon tissue with Cytokeratin 19 antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min and allow to cool before testing.
Availability 1-2 weeks
Species Reactivity Human, Rat
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name CCO-11
Purity Affinity purified
UniProt P08727
Localization Cell membrane, cytoplasmic
Applications Western blot : 1:5000-1:10000
Immunohistochemistry (FFPE) : 1:50-1:200
Limitations This Cytokeratin 19 antibody is available for research use only.
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Description

The protein encoded by the KRT19 gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. [RefSeq]

Application Notes

Optimal dilution of the Cytokeratin 19 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Cytokeratin 19 / KRT19 was used as the immunogen for the Cytokeratin 19 antibody.

Storage

Store the Cytokeratin 19 antibody at -20oC.

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