- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Cytochrome P450 2E1 Antibody / CYP2E1 [clone AADC-3] (RQ5118)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ5118 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | AADC-3 |
| Purity | Affinity purified |
| UniProt | P05181 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This Cytochrome P450 2E1 antibody is available for research use only. |
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The CYP2E1 gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer. [RefSeq]
Optimal dilution of the Cytochrome P450 2E1 antibody should be determined by the researcher.
A synthetic peptide specific to human CYP2E1 was used as the immunogen for the Cytochrome P450 2E1 antibody.
Store the Cytochrome P450 2E1 antibody at -20oC.
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