CYLD Antibody / Cylindromatosis Antibody (R33641)

CYLD Antibody Rat Brain WB. Western blot testing of rat brain lysate using CYLD antibody detected a prominent band at approximately 125 kDa. Although the predicted molecular weight of CYLD is approximately 107 kDa, slower migration has been reported and may reflect post-translational modifications or altered electrophoretic mobility. This CYLD Antibody, also called a Cylindromatosis Antibody, is useful for investigating deubiquitination, NF-kappa B signaling, inflammatory regulation, and tumor suppressor function.

CYLD Antibody Mouse Brain IHC. Immunohistochemical staining of FFPE mouse brain tissue using CYLD antibody demonstrated predominantly cytoplasmic staining of neuronal cells, consistent with the expression of CYLD in the central nervous system where it regulates ubiquitin-dependent signaling pathways. Heat-induced epitope retrieval was performed by steaming tissue sections in pH6 citrate buffer prior to staining, and immunoreactivity was visualized using an alkaline phosphatase (AP) detection system. This CYLD Antibody, also called a Cylindromatosis Antibody, is useful for investigating deubiquitination, neuronal signaling, inflammatory regulation, and tumor suppressor function.