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Home >> Antibodies >> Cyclin E1 Antibody / CCNE1

Cyclin E1 Antibody / CCNE1 [clone CCNE1/2587] (V8192)

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  Catalog No Formulation Size Price (USD)  
Image V8192-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V8192-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V8192SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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SDS-PAGE analysis of purified, BSA-free Cyclin E1 antibody (clone CCNE1/2587) as confirmation of integrity and purity.
SDS-PAGE analysis of purified, BSA-free Cyclin E1 antibody (clone CCNE1/2587) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG
Clone Name CCNE1/2587
Purity Protein G affinity chromatography
UniProt P24864
Applications ELISA (order BSA-free format for coating) :
Limitations This Cyclin E1 antibody is available for research use only.
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Description

Cyclin E belongs to the highly conserved cyclin family, whose members exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclins function as regulators of CDK kinases. Cyclin E forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. Cyclin E accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Cyclin E overexpression has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis.

Application Notes

Optimal dilution of the Cyclin E1 antibody should be determined by the researcher.

Immunogen

A recombinant human partial protein (amino acids 10-176) was used as the immunogen for this Cyclin E1 antibody.

Storage

Store the Cyclin E1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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