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Home >> Antibodies >> CXCL7 Antibody / PPBP / NAP-2

CXCL7 Antibody / PPBP / NAP-2 (RQ4113)

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  Catalog No Formulation Size Price (USD)  
Image RQ4113 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of mouse 1) bone marrow, 2) lung and 3) spleen lysate with CXCL7 antibody at 0.5ug/ml. Predicted molecular weight: 8~14 kDa.
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Western blot testing of mouse 1) bone marrow, 2) lung and 3) spleen lysate with CXCL7 antibody at 0.5ug/ml. Predicted molecular weight: 8~14 kDa.
IHC testing of FFPE mouse spleen tissue with CXCL7 antibody at 1ug/ml. Required HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to testing.
Availability 1-3 business days
Species Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt Q9EQI5
Localization Secreted
Applications Western Blot : 0.5-1ug/ml
Immunohistochemistry (FFPE) : 1-2ug/ml
Direct ELISA : 0.1-0.5ug/ml
Limitations This CXCL7 antibody is available for research use only.
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Description

Chemokine (C-X-C motif) ligand 7 (CXCL7), also known as NAP2 or Pro-Platelet basic protein (PPBP), is a human gene. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Furthermore, the protein is an antimicrobial protein with bactericidal and antifungal activity.

Application Notes

Optimal dilution of the CXCL7 antibody should be determined by the researcher.

Immunogen

A recombinant mouse partial protein corresponding to amino acids K40-Y113 was used as the immunogen for the CXCL7 antibody.

Storage

After reconstitution, the CXCL7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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