Cx40 Antibody / Connexin 40 / GJA5 (F55078)

Cx40 Antibody Human and Mouse WB. Western blot analysis of human Jurkat and HepG2 cell lysates together with mouse brain tissue lysate using Cx40 antibody demonstrates detection of a prominent immunoreactive band at approximately 40 kDa, consistent with the expected molecular weight of Connexin 40 (Cx40/GJA5). Cx40 is a gap junction protein that forms intercellular channels enabling the direct exchange of ions and signaling molecules between neighboring cells. The observed expression across both human and mouse samples supports the utility of this antibody for studies of gap junction biology, intercellular communication, cardiovascular signaling, and connexin-mediated cellular regulation. Predicted molecular weight: ~40 kDa.

Cx40 Antibody Human Placenta WB. Western blot analysis of human placental tissue lysate using Cx40 antibody demonstrates detection of a distinct immunoreactive band at approximately 40-45 kDa, consistent with the expected molecular weight of Connexin 40 (Cx40/GJA5). Connexin 40 is a transmembrane gap junction protein that forms intercellular channels facilitating the direct exchange of ions, metabolites, and signaling molecules between neighboring cells. The observed band supports expression of Cx40 in placental tissue and demonstrates the utility of this antibody for studies of gap junction biology, intercellular communication, tissue homeostasis, and connexin-mediated signaling pathways. Predicted molecular weight: ~40 kDa.

Cx40 Antibody Human Stomach IHC. Immunohistochemistry staining of FFPE human stomach tissue using Cx40 antibody demonstrates widespread cytoplasmic and membranous staining throughout gastric epithelial cell populations, consistent with expression of Connexin 40 (Cx40/GJA5). Cx40 is a gap junction protein that forms intercellular channels facilitating the direct exchange of ions, metabolites, and signaling molecules between neighboring cells. The observed staining pattern is consistent with the role of connexin proteins in coordinating cell-to-cell communication, maintaining tissue organization, and supporting physiologic homeostasis within epithelial tissues. These findings support the utility of Cx40 antibody for studies of gap junction biology, intercellular communication, and connexin-mediated signaling pathways. HIER: steam section in pH9 EDTA buffer for 20 min and allow to cool prior to staining.