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Home >> Antibodies >> CSTA Antibody / Cystatin A

CSTA Antibody / Cystatin A [clone rCSTA/8995] (V4984)

  Catalog No Formulation Size Price (USD)  
Image V4984-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4984-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4984SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recmousemono
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Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Mouse Monoclonal
Isotype Mouse IgG2b, kappa
Clone Name rCSTA/8995
Purity Protein A/G affinity
UniProt P01040
Localization Cell Surface, Cytoplasm, Nucleus
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This CSTA antibody is available for research use only.
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Description

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Application Notes

Optimal dilution of the CSTA antibody should be determined by the researcher.

Immunogen

A recombinant fragment of human protein (around aa 1-98) was used as the immunogen for the CSTA antibody.

Storage

Aliquot the CSTA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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