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Home >> Antibodies >> COX IV Antibody / COX4I1

COX IV Antibody / COX4I1 [clone AIC-3] (RQ5400)

  Catalog No Formulation Size Price (USD)  
Image RQ5400 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
Microvalidated Rab Mono Image
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Western blot testing of human HepG2 cell lysate with COX IV antibody. Predicted molecular weight ~20 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AIC-3
Purity Affinity purified
UniProt P13073
Applications Western blot : 1:1000-1:2000
Limitations This COX IV antibody is available for research use only.
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Description

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [RefSeq]

Application Notes

Optimal dilution of the COX IV antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human COX IV / COX4I1 was used as the immunogen for the COX IV antibody.

Storage

Store the COX IV antibody at -20oC.

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