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Home >> Antibodies >> Collagen VI Antibody / COL6A1

Collagen VI Antibody / COL6A1 [clone HGG-3] (RQ5382)

  Catalog No Formulation Size Price (USD)  
Image RQ5382 Antibody in PBS with 0.02% sodium azide and 50% glycerol 100 ul 429
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Western blot testing of human brain lysate with Collagen VI antibody. Predicted molecular weight ~109 kDa, routinely observed at 140-150 kDa.
Western blot testing of rat kidney lysate with Collagen VI antibody. Predicted molecular weight ~109 kDa, routinely observed at 140-150 kDa.
Availability 1-2 weeks
Species Reactivity Human, Mouse, Rat
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name HGG-3
Purity Affinity purified
UniProt P12109
Applications Western blot : 1:1000-1:2000
Limitations This Collagen VI antibody is available for research use only.
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Description

The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [RefSeq]

Application Notes

Optimal dilution of the Collagen VI antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Collagen VI / COL6A1 was used as the immunogen for the Collagen VI antibody.

Storage

Store the Collagen VI antibody at -20oC.

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