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Home >> Antibodies >> CNIH2 Antibody

CNIH2 Antibody (F54600)

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  Catalog No Formulation Size Price (USD)  
Image F54600-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F54600-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC testing of FFPE human brain tissue with CNIH2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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IHC testing of FFPE human brain tissue with CNIH2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Immunofluorescent staining of human U-251 MG cells with CNIH2 antibody (green) and DAPI nuclear stain (blue).
Western blot testing of human HL60 cell lysate with CNIH2 antibody. Predicted molecular weight ~19 kDa.
Flow cytometry testing of human HL60 cells with CNIH2 antibody; Blue=isotype control, Green= CNIH2 antibody.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity purified
UniProt Q6PI25
Localization Cytoplasmic
Applications Western blot : 1:500-1:2000
Immunohistochemistry (FFPE) : 1:25
Flow cytometry : 1:25 (1x10e6 cells)
Immunofluorescence : 1:25
Limitations This CNIH2 antibody is available for research use only.
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Description

Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. [UniProt]

Application Notes

The stated application concentrations are suggested starting points. Titration of the CNIH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 31-59 from the human protein was used as the immunogen for the CNIH2 antibody.

Storage

Aliquot the CNIH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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