CLU Antibody / Cytoprotective Stress Response Marker [clone CLU/4727] (V9337)

CLU Antibody Adrenal Gland IHC. Immunohistochemistry analysis of FFPE human adrenal gland tissue using CLU antibody. The mouse monoclonal antibody clone CLU/4727 demonstrates cytoplasmic staining in glandular cells, consistent with Clusterin / CLU expression as a cytoprotective stress response marker. Signal is observed within adrenal cortical cell populations, reflecting stress-associated upregulation of this secreted chaperone protein, while surrounding stromal elements show lower staining. HIER: boil tissue sections in 10 mM Tris with 1 mM EDTA, pH 9, for 20 min followed by cooling prior to staining.

CLU Antibody Testis WB. Western blot analysis of human testis tissue lysate using CLU antibody. The mouse monoclonal antibody clone CLU/4727 detects bands at approximately 75-80 kDa and lower molecular weight bands around 34-39 kDa, consistent with the predicted molecular weight of full-length Clusterin / CLU and its processed alpha and beta subunits. This banding pattern reflects proteolytic cleavage and glycosylation of this secreted chaperone protein, supporting its role as a cytoprotective stress response marker in western blot analysis.

CLU Antibody Protein Microarray Specificity Validation. Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using CLU antibody. The mouse monoclonal antibody clone CLU/4727 shows a strong and specific signal for Clusterin / CLU, with a high Z-score and clear separation from non-target proteins, supporting its specificity as a cytoprotective stress response marker. The Z-score reflects signal intensity above background, while the S-score indicates the degree of separation from the next highest signal, confirming selective binding to the intended target.

SDS-PAGE analysis of purified, BSA-free CLU antibody (clone CLU/4727) as confirmation of integrity and purity.