- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CLEC1 Antibody (N1092)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
N1092-100UG | 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 429 | |
|
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N1092-25UG | 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 25 ug | 219 |
|
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Protein A purified antibody |
| Buffer | 1X PBS, pH 7.4 |
| Gene ID | 51267 |
| Applications | Western blot : 2-5ug/ml |
| Limitations | This CLEC1 antibody is available for research use only. |
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CLEC1 is a C-type lectin receptor and part of the ‘Dectin-1 cluster’ subfamily which also includes Dectin-1, LOX-1, CLEC-2, MICL, CLEC12B, and CLEC9A. Similar to other family members, CLEC1 displays N-liked glycosylation and dimerization characteristics, and is found on dendritic cells, monocytes and granulocytes. However, unlike other family members, CLEC1 expression level is upregulated by IL-10 and TGFb, but not by pro-inflammatory stimuli, and it is expressed on endothelial cells. Enhanced expression at allograft sites suggests CLEC1 may have an immune-regulatory function and may support allograft tolerance.
Provided assay concentrations are suggestions only, CLEC1 antibody titration may be required for optimal results.
A recombinant protein fragment from the N-terminal portin of human CLEC1 was used as the immunogen for this antibody.
Aliquot the CLEC1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
C-type lectin-like receptor 1 antibody
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