- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
CLDN1 Antibody / Claudin 1 [clone ABEH-3] (RQ4817)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ4817 | Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA | 100 ul | 429 |
|
| Availability | 1-2 weeks |
| Species Reactivity | Human |
| Format | Purified |
| Clonality | Rabbit Monoclonal |
| Isotype | Rabbit IgG |
| Clone Name | ABEH-3 |
| Purity | Affinity purified |
| UniProt | O95832 |
| Applications | Western blot : 1:500-1:2000 |
| Limitations | This CLDN1 antibody is available for research use only. |
|
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Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. [UniProt]
Optimal dilution of the CLDN1 antibody should be determined by the researcher.
A synthetic peptide specific to human Claudin 1 / CLDN1 was used as the immunogen for the CLDN1 antibody.
Store the CLDN1 antibody at -20oC.
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