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Home >> Antibodies >> CK1 Antibody / Cytokeratin 1 / Keratin 1

CK1 Antibody / Cytokeratin 1 / Keratin 1 [clone KRT1/1840] (V7908)

  Catalog No Formulation Size Price (USD)  
Image V7908-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7908-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7908SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human cervical carcinoma with CK1 antibody (clone KRT1/1840). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human skin with CK1 antibody (clone KRT1/1840). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free CK1 antibody (clone KRT1/1840) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human, Rat
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name KRT1/1840
Purity Protein G affinity chromatography
UniProt P04264
Localization Cytoplasmic
Applications Immunohistochemistry (FFPE) : 2-4ug/ml
Limitations This CK1 antibody is available for research use only.
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Description

Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.

Application Notes

Optimal dilution of the CK1 antibody should be determined by the researcher.

Immunogen

A recombinant full-length human Cytokeratin 1 protein was used as the immunogen for this CK1 antibody.

Storage

Store the CK1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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