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Home >> Antibodies >> cIAP2 Antibody

cIAP2 Antibody (R32217)

  Catalog No Formulation Size Price (USD)  
Image R32217 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 419
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Western blot testing of human 1) HepG2 and 2) HeLa lysate with cIAP2 antibody. Predicted/observed molecular weight ~68 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt Q13489
Applications Western blot : 0.1-0.5ug/ml
Limitations This cIAP2 antibody is available for research use only.
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Description

Baculoviral IAP repeat-containing protein 3 (also known as cIAP2) is a protein that in humans is encoded by the BIRC3 gene. cIAP2 is a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

Application Notes

Optimal dilution of the cIAP2 antibody should be determined by the researcher.

Immunogen

Amino acids 1-191 of human cIAP2 were used as the immunogen for the cIAP2 antibody.

Storage

After reconstitution, the cIAP2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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