- Tel: 858.663.9055
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Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Ceruloplasmin Antibody / CP (R31856)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
|
R31856 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 439 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| UniProt | P00450 |
| Localization | Cytoplasmic |
| Applications | Western Blot : 0.5-1ug/ml Flow Cytometry : 1-3ug/million cells |
| Limitations | This Ceruloplasmin antibody is available for research use only. |
|
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Ceruloplasmin (CP) is a copper-binding glycoprotein primarily synthesized in the liver and secreted into the plasma. It plays an essential role in iron metabolism by oxidizing Fe2+ to Fe3+, facilitating its binding to transferrin for transport. Beyond its ferroxidase activity, Ceruloplasmin functions as an antioxidant and contributes to copper transport, wound healing, and defense against oxidative stress.
CP is widely expressed in various tissues and is present in high concentrations in the blood. Its regulation is influenced by physiological states such as pregnancy, inflammation, and hormonal changes. Due to its multifunctional nature, Ceruloplasmin has been a focus of studies in biochemistry, nutritional science, and oxidative stress biology.
The Ceruloplasmin antibody is a reliable tool for detecting CP in applications including western blot, immunohistochemistry, and ELISA. Researchers use the Ceruloplasmin antibody from NSJ Bioreagents to evaluate protein expression levels, study tissue distribution, and explore its roles in metal ion homeostasis and oxidative defense mechanisms. With high specificity and reproducible performance, the Ceruloplasmin antibody supports a wide range of research in molecular biology, metabolism, and protein biochemistry.
Optimal dilution of the Ceruloplasmin antibody should be determined by the researcher.
Amino acids 20-259 of human Ceruloplasmin were used as the immunogen for the Ceruloplasmin antibody.
After reconstitution, the Ceruloplasmin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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