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Home >> Antibodies >> CEBPB Antibody

CEBPB Antibody (F49889)

  Catalog No Formulation Size Price (USD)  
F49889-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 329

F49889-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 135
Western blot analysis of CEBPB antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected with the CEBPB gene (2). Predicted molecular weight: ~36kDa (human).
IHC analysis of FFPE human lung carcinoma stained with CEBPB antibody
CEBPB antibody flow cytometric analysis of 293 cells (green) compared to a negative control (blue). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Bovine, Chicken, Mouse, Rat
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P17676
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Limitations This CEBPB antibody is available for research use only.
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Description

CEBPB is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. This protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, It can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.

Application Notes

Titration of the CEBPB antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 271-298 from the human protein was used as the immunogen for this CEBPB antibody.

Storage

Aliquot the CEBPB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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