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Home >> Antibodies >> Cdk7 Antibody

Cdk7 Antibody (R31240)

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  Catalog No Formulation Size Price (USD)  
Image R31240 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of Cdk7 antibody and Lane 1: HeLa; 2: MCF-7; 3: A549; 4: COLO320; 5: Jurkat cell lysate. Expected/observed molecular weight ~37 kDa.
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Western blot testing of Cdk7 antibody and Lane 1: HeLa; 2: MCF-7; 3: A549; 4: COLO320; 5: Jurkat cell lysate. Expected/observed molecular weight ~37 kDa.
Western blot testing of Cdk7 antibody and Lane 1: rat testis; 2: rat ovary tissue lysate. Expected/observed molecular weight ~37 kDa.
Availability 1-3 business days
Species Reactivity Human, Rat, Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P50613
Applications Western blot : 0.5-1ug/ml
Limitations This Cdk7 antibody is available for research use only.
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Description

Cyclin-dependent kinase 7, also known as Cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase(CDK) family. The gene was assigned to human chromosome 5q13.2. Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex. It is required for DNA-bound peptides-mediated transcription and cellular growth inhibition.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the Cdk7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the C-terminus of human Cyclin-dependent kinase 7 (RKRTEALEQGGLPKKLIF) was used as the immunogen for this Cdk7 antibody.

Storage

After reconstitution, the Cdk7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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