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Home >> Antibodies >> CDK1 Antibody / CDC2

CDK1 Antibody / CDC2 [clone CDVC2-1] (V7171)

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  Catalog No Formulation Size Price (USD)  
Image V7171-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7171-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7171SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Western blot testing of human HeLa cell lysate with CDK1 antibody (clone CDVC2-1). Predicted molecular weight ~33 kDa.
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Western blot testing of human HeLa cell lysate with CDK1 antibody (clone CDVC2-1). Predicted molecular weight ~33 kDa.
IHC testing of FFPE human tonsil with CDK1 antibody (clone CDVC2-1). Staining of formalin-fixed tissues requires boiling tissue sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min followed by cooling at RT for 20 min.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a, kappa
Clone Name CDVC2-1
Purity Protein G affinity chromatography
UniProt P06493
Localization Nuclear and cytoplasmic
Applications Western blot : 1-2ug/ml
Immunohistochemistry (FFPE) : 2-4ug/ml for 30 min at RT
Limitations This CDK1 antibody is available for research use only.
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Description

Cyclin-Dependent Kinase 1 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. [RefSeq]

Application Notes

Titering of the CDK1 antibody may be required for optimal performance.

Immunogen

Recombinant human protein was used as the immunogen for the CDK1 antibody.

Storage

Store the CDK1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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