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Home >> Antibodies >> Cdc37 Antibody

Cdc37 Antibody (R32244)

  Catalog No Formulation Size Price (USD)  
Image R32244 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human 293 cell lysate with Cdc37 antibody. Expected/observed molecular weight 44~50 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt Q16543
Applications Western blot : 0.1-0.5ug/ml
Limitations This Cdc37 antibody is available for research use only.
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Description

Hsp90 co-chaperone Cdc37, also called P50CDC37, is a protein that in humans is encoded by the CDC37 gene. The protein encoded by this gene is highly similar to cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This gene is mapped to 19p13.2. And this protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases.

Application Notes

Optimal dilution of the Cdc37 antibody should be determined by the researcher.

Immunogen

Amino acids 216-378 of human Cdc37 were used as the immunogen for the Cdc37 antibody.

Storage

After reconstitution, the Cdc37 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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