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Home >> Antibodies >> Cdc25c Antibody

Cdc25c Antibody (RQ6244)

  Catalog No Formulation Size Price (USD)  
Image RQ6244 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of rat pancreas tissue lysate with Cdc25c antibody. Predicted molecular weight ~53 kDa.
Availability 1-3 business days
Species Reactivity Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P48967
Applications Western blot : 1-2ug/ml
Limitations This Cdc25c antibody is available for research use only.
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Description

M-phase inducer phosphatase 3 is an enzyme that in humans is encoded by the CDC25C gene. This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis. Also, it is thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Application Notes

Optimal dilution of the Cdc25c antibody should be determined by the researcher.

Immunogen

A mouse recombinant partial protein (amino acids K24-Q447) was used as the immunogen for the Cdc25c antibody.

Storage

After reconstitution, the Cdc25c antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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