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Home >> Antibodies >> Cdc25A Antibody

Cdc25A Antibody (F49547)

  Catalog No Formulation Size Price (USD)  
Image F49547-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49547-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Cdc25A antibody western blot analysis in MCF-7 lysate. Predicted molecular weight: 59-70 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Bovine, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P30304
Applications Western blot : 1:1000
Limitations This Cdc25A antibody is available for research use only.
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Description

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.

Application Notes

Titration of the Cdc25A antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 57-84 from the human protein was used as the immunogen for this Cdc25A antibody.

Storage

Aliquot the Cdc25A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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