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Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro. [UniProt]
The stated application concentrations are suggested starting amounts. Titration of the Cdc25A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 271-300 from the human protein was used as the immunogen for this Cdc25A antibody.
Store at 4oC for up to one month. For long term, aliquot the Cdc25A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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